Robust Inference for Incomplete Binary Longitudinal Data
Missing data occur in many longitudinal studies. When data are nonignorably missing, it is necessary to incorporate the missing data mechanism into the observed data likelihood function. A full likelihood analysis of nonignorable missing data is complicated algebraically, and often requires intensive computation, especially when there are many follow-up times. To avoid such computational difficulties, pseudo-likelihood methods have been proposed in the literature under minimal parametric assumptions. However, like the classical maximum likelihood estimators, these pseudo-likelihood estimators are also sensitive to potential outliers in the data. In this article, we propose and explore a robust method in the framework of a pseudo-likelihood function that is derived under the working assumption that the longitudinal responses are independent over time. The performance of the proposed robust method is investigated in simulations. The method is also illustrated in an example using actual data on CD4 counts from clinical trials of HIV-infected patients.
- There are currently no refbacks.
If you have already registered in Journal A and plan to submit article(s) to Journal B, please click the CATEGORIES, or JOURNALS A-Z on the right side of the "HOME".
We only use the follwoing mailboxes to deal with issues about paper acceptance, payment and submission of electronic versions of our journals to databases:
Copyright © 2010 Canadian Research & Development Center of Sciences and Cultures
Address: 758, 77e AV, Laval, Quebec, Canada H7V 4A8
Telephone: 1-514-558 6138
E-mail:firstname.lastname@example.org email@example.com firstname.lastname@example.org