The Actinidic Archaea Related Lemurian Syndrome- Endomyocardial Fibrosis, Chronic Calcific Pancreatitis and Multinodular Goitre- Evolutionary Significance and Evidence for the Lemurian Supercontinent
Background: Endogenous digoxin has been related to the pathogenesis of chronic calcific pancreatitis, endomyocardial fibrosis, multinodular goitre and mucoid angiopathy which are seen in South India, South Africa, Australia and South America. Phytoplasmas, viroids and rutile in beach sands have been related to root wilt disease of coconut seen in the same endemic area. The possibility of endogenous digoxin synthesis by actinide based primitive organism like archaea with a mevalonate pathway and cholesterol catabolism as well as a RNA viroid role in pathogenesis of these endemic diseases was considered. The study aims to link actinidic nanoarchaea to etiology of these diseases and postulates their common geographic epidemiology to the existence of a pre-historic Lemurian supercontinent linking these geographic areas. It also postulates a role for actinidic surfaces in the evolution of life, eukaryote, primates and humans.Methods: 10 cases each of chronic calcific pancreatitis, endomyocardial fibrosis, multinodular goitre and mucoid angiopathy before starting treatment and 10 age and sex matched healthy controls from general population were chosen for the study. Cholesterol substrate was added to the plasma of the patients and the generation of cytochrome F420, free RNA, free DNA, polycyclic aromatic hydrocarbon, hydrogen peroxide, serotonin, pyruvate, ammonia, glutamate, cytochrome C, hexokinase, ATP synthase, HMG CoA reductase, digoxin and urease were studied. The changes with the addition of antibiotics and rutile to the patient’s plasma were also studied. The statistical analysis was done by ANOVA.Results: The parameters mentioned above were increased the patient’s plasma with addition of cholesterol substrate. The addition of antibiotics to the patient’s plasma caused a decrease in all the parameters while addition of rutile increased their levels. Conclusions: An actinide dependent shadow biosphere of archaea and viroids is described in endomyocardial fibrosis, chronic calcific pancreatitis, multinodular goitre and mucoid angiopathy contributing to their pathogenesis. The coexistence of EMF, CCP and MNG in South India, South Africa, Australia and South America is thus an indirect evidence for the existence of the Lemurian supercontinent containing these land masses and rich in actinidic minerals. It also is evidence of abiogenesis on radioactive actinidic beach sands through the process of surface metabolism in the course of evolution. This gives credence to the role of actinidic archaea as the third element that controls life and its role in the evolution of the multicellular eukaryote, primates and humans.
Key words: Archaea; Viroids; Endomyocardial fibrosis; Chronic calcific pancreatitis; Multinodular goitre; Mucoid angiopathy; Lemuria
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