SYNTHESIS of 1-(4-HYDROXYLPHENYL)-4-(4-NITROPHENYL)PIPERAZINE

Chang-mei KE, Ning TANG, Yong HU, Quan-quan WANG

Abstract


Triazole medicines are mainstream of the antifungal medicines, especially used in curing deep department fungal infections and its important intermediate is 1-(4-hydroxylphenyl)-4-(4-nitrophenyl)piperazine. As the key intermediate of antifungal medicines of new generation,it has already caused international interest. A general and convenient synthesis of 1-(4-hydroxylphenyl)-4-(4-nitrophenyl) piperazine without the use of catalyst is described.

Key words:  1-(4-hydroxylphenyl)-4-(4-nitrophenyl)piperazine; antifungal intermediate;  Triazole

Full Text:

PDF


DOI: http://dx.doi.org/10.3968%2Fj.ans.1715787020090201.004

Refbacks

  • There are currently no refbacks.


Reminder

How to do online submission to another Journal?

If you have already registered in Journal A, then how can you submit another article to Journal B? It takes two steps to make it happen:

1. Register yourself in Journal B as an Author

Find the journal you want to submit to in CATEGORIES, click on “VIEW JOURNAL”, “Online Submissions”, “GO TO LOGIN” and “Edit My Profile”. Check “Author” on the “Edit Profile” page, then “Save”.

2. Submission

Go to “User Home”, and click on “Author” under the name of Journal B. You may start a New Submission by clicking on “CLICK HERE”.

We only use the following emails to deal with issues about paper acceptance, payment and submission of electronic versions of our journals to databases:
caooc@hotmail.com; office@cscanada.net; office@cscanada.org
ans@cscanada.net;ans@cscanada.org

Copyright © Canadian Research & Development Centre of Sciences and Cultures (CRDCSC)
Address:730, 77e AV, Laval, Quebec, H7V 4A8, Canada

Telephone: 1-514-558 6138
Http://www.cscanada.net; Http://www.cscanada.org
E-mail:caooc@hotmail.com; office@cscanada.net